Detection of DNA induced gold nanoparticle aggregation with dark field imaging.
نویسندگان
چکیده
Dark field imaging was employed to visualize and quantify complementary DNA-induced gold nanoparticle aggregation at the single-particle level, with a detection limit of 100 fM DNA, which allows the highly sensitive detection of single nucleotide polymorphisms (SNPs). Results suggested that the aggregation process is consistent with the cluster-cluster model.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 68 شماره
صفحات -
تاریخ انتشار 2013